Latent Cytomegalovirus Infection Exacerbates Experimental Colitis

Ulcerative colitis exacerbation associated with cytomegalovirus infection.

There is an increasing prevalence of ulcerative colitis in Hong Kong and cytomegalovirus infection is an important factor in the exacerbation of the disease. We report on a 33- year-old Chinese man with ulcerative colitis in remission, who presented with bloody diarrhoea that failed to respond to an intensive regimen of oral and rectal steroid. Colonoscopy was performed and biopsy specimens sho...

Latent cytomegalovirus infection in blood donors.

Twenty-one out of 32 apparently healthy blood donors aged 21 to 65 years yielded positive complement fixation tests with a cytomegalovirus antigen, at titres ranging from 1:8 to 1:64. Virus was present in leucocyte cultures of fresh peripheral blood of two seropositive subjects from a total of 35 donors examined. Plasma and 48-hour stored blood specimens failed to disclose virus in culture. Vir...

Latent CytomegaLovirus infeCtion among eLderLy thais

We determined the seroprevalence of latent cytomegalovirus (CMV) infection among young and elderly adults to test for a change in seroprevalence with increasing age. Thirty-two young and 32 elderly adults were tested for antiCMV IgG, T-cell subgroup analysis, mental status and daily life activity. There was no significant difference in the seroprevalence of CMV infection between the two groups ...

Cytomegalovirus: a cause of persistent latent infection.

Dietary phosphate exacerbates intestinal inflammation in experimental colitis

The recent widespread consumption of Western diets and food additives worldwide is associated with excessive inorganic phosphate intake. However, researchers have known little about the impact of dietary phosphate intake on the development of inflammatory bowel disease to date. In this study, we investigated the effects of dietary phosphate on intestinal inflammation in experimental colitis. Sp...